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44 comments


  • Olivia Venter

    Hello, I missed taking a Progynova tablet abs only noticed the next morning. Will this affect anything?

    October 03, 2020
  • Shikha

    Hi I did my FET on Monday …have no symptoms of pregnancy yet.
    Really worried if it is success or not ?
    I need to take pregnancy test on 12th September.
    I am taking progestrone injections daily
    Please suggest

    September 05, 2020
  • Jane Wright

    I was I hour late with Utrogestan on day 6 of Transfer will everything be ok x

    July 24, 2020
  • Swatee

    I would like know usually in ivf treatment until what gestation week, progesterone injections are recommended ? After how many weeks a lady could stop taking it ? Usually when placental take over progesterone production?

    June 06, 2020
  • Applekafayat

    Can use more than Chyclogest per day please very urgent

    April 03, 2020
  • Kirsty Allan

    Hi I’ve just got a BFP from fresh ivf cycle at 10dp5dt my clinic had advised I don’t need to continue cyclogest pessaries now as my body will be producing progesterone at this stage. I know my clinic are the experts and I do trust what they advised but I’ve read a lot of clinics prefer patients to be on it anywhere up to 12 weeks pregnant so I am a little anxious, should I be concerned? Thank you x

    February 15, 2020
  • Yomn

    Hello I had frozen embryo transfer yesterday I fogot to take progestin injection and I had suppository 13 hours later. Could i know the sequences of this missing…

    January 19, 2020
    • Maria Ligon

      hi it happens to me i missed 2 days injection.what did the doctor tell you.pls help.thanks

      January 20, 2020
  • Tyler

    Hi all, I was unable to refill my progesterone capsules over New Years Eve and Day (as everywhere was closed), so I was told to supplement with an extra shot of the oil (I was already taking 1 1mL injection daily, so took 1 extra shot each day). I am back on the capsule + injection regimen, but I’m worried I have jeopardized the pregnancy. Has anyone been thru something similar or know if this short term supplementation can work out ok?

    January 02, 2020
  • Niharika

    I got positive result after embryo transfer I’m using vaginal progestron tablets so how long I should use progestron tablets

    December 30, 2019
    • Jennifer

      My doctor advised till the 28th week. You could also confirm from yours. God speed

      January 29, 2020
  • K

    I took a test 9 days after 5 day transfer the test was negative but I am 7 days late on my period is there any chance I could still be pregnant as previous test a week ago gave a faint positive or could the pesseries just be delaying my period please help

    December 26, 2019
    • Ruby

      Hi there, I had a similar situation. I took a test on the 7th day after my 5 day blastocyst transfer and it showed negative but with an ever so very faint positive line. I took it again on the 14th day as I was told by my clinic and it showed up positive.

      I think it’s best to consult your fertility clinic for advice and a blood test to confirm. I have to go later this week to do that. I know it’s super stressful to not know or be certain but they are the professionals and should be providing you with the right advice and care:). Goodluck and I am sending positive vibes over

      December 31, 2019
  • syeda fatima

    hey A.A
    I have taken iui treatment this month on 13,14 Nov 2019. today i forgot taking cyclogest in morning
    now i took it but i suppose to take 2nd dose in midnight
    does it work?

    November 23, 2019
  • Ola

    Hi
    I have a question, this is my first ivf and I did my transfer on the first of April, after 14days I went for my first appointment which was positive and I was told to come in two weeks time for first scan and when the scan was carried out they found out that the embryo is not found in the sac, pls what could be the reason or is it something to worry about. Thanks

    May 06, 2019
  • Lucy

    Hii, i have gone through my FET i have been taking endometrin 100 mg 4 times a day and prontogest inject once a day, 2 days before doc did my test progestrone and E2 level that came p-20 E2-212 , should it be good level for pregnancy? Am i pregnant could you tell me about it what should be the level?

    April 23, 2019
  • Dan staffo

    What number to RE’s like to see when doing progesterone shots and taken vaginally ? 3 days before beta my wife’s at 20. 28 . Is this good or at a exceptable level? Thanks for any help

    July 06, 2018
  • Samantha

    Hi, I have my transfer tomorrow morning at 8:30am. Do I take my pessary in the morning before the transfer and if so at what time?
    Thank you

    July 06, 2018
  • ananta

    What should be the right progesterone supplementation in IVF OD pregnancy,particularly in 1st 2nd & 3rd trimesters of pregnancy,please guide?

    May 31, 2018
  • Joseph Yompab

    what happens when you miss the injection for three times in the process pls.

    November 17, 2017
  • Lynnn

    Hi I’ve done my fet done October 5 but the thing is only stuffy nose is very annoying while I’m sleeping at night and aside from that nothing my test is on 16th of October I’m wondering is anyone got the same condition? Thanks

    October 11, 2017
    • Heather

      Glad I’m not the only one who has a stuffy nose taking progesterone!! I thought I was going crazy!

      February 22, 2018
  • joyous

    im pregnant from ivf .So what i want to know is how long must i use cyclogest

    July 25, 2017
  • Sadie

    Hi I had my frozen embryo transfer on the 2nd
    June. I done a home pregnancy test this afternoon and it was negative, I’m devastated.
    Is it possible that it could be wrong as I was impatient and tested two days early!

    This is our 3rd round, first we miscarriaged and second it did not catch. We have put two in this time.

    Feeling so heartbroken right now with life.

    June 10, 2017
    • To Sadie

      Be strong.

      June 26, 2017
    • Laura

      It can absolutely be too early to get a positive. What test did you use hun? X

      August 18, 2017
    • Laura

      So sorry, just seen this is from June x

      August 18, 2017
  • Rg

    Hello ladies! After 3 embryo transfer I’m on 600mg Utrogestan per day, orally, and a 25mg shot of Prolutex in the morning. (I’m almost 42 years old, and this is our 2nd ivf attempt with my own eggs.) Sometimes I get dizzy for half and hour or so after having taken orally a 200mg pill of Utrogestan, sometimes not. But what worries me is that Prolutex gives me a rash in the chest area. I spoke to my doctor about it and he said that it can’t be from Prolutex, well, I know my body better than that, no allergies so far by any reason, and it can’t be a coincidence that the day I started Prolutext the rash appeared, in both ivf cycles. Anyone with the same reaction?
    I was aslo prescribed Salospir, but after reminding my doctor about my ulcerative colitis case he decided that it’s not necessary to take it or any other drug instead of it. I asked about flaxseed oil, he said no. Any thoughts about that?
    Good luck to everyone!!!

    May 03, 2017
    • Debbie

      Hey, I’m on 600mg utrogestan vaginally (6dp5dt of our first Donor egg/sperm cycle) and also have a rash on my chest and arm. We had our treatment in Spain and just assumed the rash was prickly heat, but it hasn’t gone away. Could be the utrogestan causing it for us both?!

      May 09, 2017
  • Sani

    When do you usually stop the progesterone gel suppositories?

    March 30, 2017
  • Liqaa

    I have done IVF 14 days ago I have done blood test HCG results 35, and from 1st day after the IVF Dr asked me to take below medication on daily basis isn’t too much medication can you tell me that if its okay if i can take it?
    – folic acid 5mg tablet one daily
    – vitamin B6 tablet one daily
    – Cyclogest Suppositories 400 mg vaginal use twice daily
    – Estrofem tablet 2mg twice daily
    – Prednisolone tablets 5 mg 2 tablet twice daily
    – Clexane 4000 injection daily under the skin in the stomach one daily
    – Duphaston 10 mg tablets 3 times daily
    – B12 on daily basis 400iu

    February 11, 2017
  • Maria

    Thanks for the information. I’m doing IVF -(PGD), and the transfer of the frozen embryos is in three days- Tuesday. I was supposed to start utrogestan one day ago- Friday and I completely forgot. I started today, and I’m taking two in the morning and two at night. Do you think that’s going to ruin my chances of getting pregnant?

    February 11, 2017
  • Aru

    I was supposed to take Utrogestan at 8am and 8pm.. i forgot the night dose and took it an hour late i.e. at 9pm. Will this impact the outcome. This is day 11 post FET

    December 28, 2016
  • Taati

    Hi all, am using utrogestan 200 gel (3 times a day) in the vigina . Am on my 6th day since embroyo tranfer, i see no sign of discharge but my gel comes out quet often?
    Should i be worried

    December 17, 2016
  • lara

    I have a question. I am first time ivf.one egg. It was the 13th day post transfer when i saw blood when cleaning myself on the toilet. I have had brownish discarg for 2 days.each day a bit more. In the afternoon after estima i got brownish spotting again. I am very confused cause its changing from blood to brown. Do you think that my body is lacking of progesterone? I am taking pills into vagina. When i lay down its mostly brown but when i move around i het blood.or its my period and the progesterone is stopping the period to come? Is that possible? My periods or heavy? Changing every hour ussualy,my pads.today is the 14th day and i have blèed a bit but its far from what i would call my period.i jad one pad the whole day.after taking the second progesterone there was brown discarge instead of blood. And when i put in the last pill for today in the vagina my finger was clear.no blood on it like in the morning.i have my blood test tomorrow and i doubt i will get any explenaction from my hospital.i am just a number there.

    December 03, 2016
    • Rezwana Chowdhury

      What was your result?

      April 18, 2017
  • Jenny

    I’ll be going for ET in a week’s time. My hospital normally administers cyclogest few days before ET and continues after the transfer. My last procedure failed.Having heard so much about progesterone injections, am considering giving it a try. My question now is this: Has anyone started with cyclogest and later switched over to progesterone injection or can one do the two at the same time just to maximize success.

    December 02, 2016
  • Jenny

    Marianna, how far along are you pls.

    November 28, 2016
  • Collette

    Can pessaries hurt the baby if you do 2 at once as my Dr told me to use 2 at night and iv just found out the should not be taken that way please tell me have I hurt my baby

    October 29, 2016
  • Irinita

    Has anybody used prontogest and crinone at the same time? I had two previous transfers and used only prontogest (one injection per day). Both pregnancies ended in a miscarriage. I’ve now had another transfer and I’ve been checking my beta hcg since day 10 of the transfer and it is doubling as required. I had some cramping and some spotting about 5 days before my scheduled period (which is due on 14.10). I’m very anxious that not having enough progesterone in my body, I may start the period and the pregnancy will be expelled. I asked my doctor if I could add crinone in addition to prontogest but had no definitive answer… I was told that additional dosage of progesterone will not harm the baby. I am very keen to do everything to stop the uterus contractions so that a healthy pregnancy proceeds.

    October 13, 2016
    • Marianna

      Yes, actually I was on a triple progesterone support – gel, injection and pills.

      October 28, 2016
  • Nancy

    Hi. Thanks for the info. Due to a mix-up at my clinic, I have been using a 1/2″ needle for my PIO injections from 5 days prior to FET (suppression cycle) until the mistake was realized and corrected 3.5 days after FET. Will any of that PIO have made it to where it needs to be, or did I just blow my one and only chance at pregnancy? I am a thin and muscular person, if that helps. Thanks.

    August 06, 2016
  • RichC

    great site. easy to read.
    One thing … you mention PROLUTEX subcutaneous progesterone . it’s not called that in UK .
    in the UK it is called LUBION

    July 22, 2016
  • Neil

    Fantastic site. A few minutes reading / watching the videos answered all our questions. Thank you.

    December 13, 2015

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